2. Peptide ligand-receptor pair involved in plant growth and development

Peptide ligand-receptor pair involved in plant growth and development

  • School of Science/Graduate School of Science
  • Division of Biological Science
  • Laboratory of Developmental Biology
  • Group of Intercellular Signaling Biology

Yoshikatsu Matsubayashi [Professor]


Outline of Seeds

Cell-to-cell signaling mediated by secreted signals and membrane-localized receptors is one of the critical mechanisms by which growth and development of multicellular organisms are cooperatively regulated. Signal molecules that specifically bind receptors are generally referred to as ligands. Because membrane-localized receptors act as master switches of complex intracellular signaling, identification of the ligand-receptor pair is one of the central issues of post-genome research. We are working to clarify the mechanisms by which plant development is regulated through identification of novel ligands such as small peptides and their specific receptors using Arabidopsis genome information, biochemical analysis and phenotypic observation.

Monographs, Papers and Articles

  • Tabata R., Sumida K., Yoshii T., Ohyama K., Shinohara H., Matsubayashi Y. Perception of root-derived peptides by shoot LRR-RKs mediates systemic N-demand signaling Science 346, 343-346 (2014)
  • Matsuzaki Y., Ogawa-Ohnishi M., Mori A., Matsubayashi Y. Secreted peptide signals required for maintenance of root stem cell niche in Arabidopsis. Science 329, 1065-1067 (2010)
  • Ogawa M., Shinohara H., Sakagami Y., Matsubayashi Y. Arabidopsis CLV3 peptide directly binds CLV1 ectodomain. Science 319, 294 (2008)
  • Matsubayashi Y., Ogawa M., Morita A., Sakagami Y. An LRR receptor kinase involved in perception of a peptide plant hormone, phytosulfokine. Science 296, 1470-1472 (2002)